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Researchers have doubled their estimate of how many cases of breast cancer are caused yearly by HRT use in the UK. The study was an international collaboration led by Oxford University and funded by Cancer Research UK. Here I explain what this means for women worried about being on this medication.
500,000 women were involved in the study over a 26-year period, from 1992 to 2018. The results showed that:
The Medicines and Healthcare products Regulatory Agency (MHRA) are advising women who are on HRT to be particularly vigilant for signs of changes to their breasts, and to talk their doctor about the revised risks when renewing their prescription of HRT.
The MHRA are also advising that:
This is something that women need to discuss with their doctors, to thoroughly assess the risks and benefits, as per the MHRA's advice.
Our advice is that women who wish to come off HRT do so as slowly as possible, preferably over a year or more, to reduce the symptoms caused by sudden withdrawal.
Menopause Support and other isoflavone products are natural and gentle. They give oestrogenic support that is not associated with increased risk of cancer, thyroid issues, or cardiovascular problems. They do not, however constitute a direct equivalent to HRT. Their strength is far less than that of HRT, and women swapping from HRT to Menopause Support will experience withdrawal effects from the HRT. The more suddenly HRT is stopped, the more extreme these withdrawal effects are likely to be.
This should be discussed with the woman's doctor, to help understand the balance of risk and benefit to that woman.
No. All the research relating to isoflavone supplementation shows no increased risk of cancer.
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